Ethylene Glycol → 2-hydroxyethyl 3-(N-vinylformamido)propionate
反応式
[CH:1]([N:3]([CH2:6][CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH:4]=[O:5])=[CH2:2].C(O)C[OH:15].C[O-].[Na+].C(O)C>CO>[CH:1]([N:3]([CH2:6][CH2:7][C:8]([O:10][CH2:11][CH2:12][OH:15])=[O:9])[CH:4]=[O:5])=[CH2:2]参加物
6
反応条件
- 温度
- 90 °C
実験手順
The apparatus of Example 2 was charged with 17.1 grams (0.1 mol) of ethyl 3-(N-vinylformamido)propionate, 6.2 grams (0.1 mol) of ethylene glycol, and 0.15 gram of 25% sodium methoxide in methanol solution. The mixture was stirred at 90° C. for 2 hours. No evolution of ethanol was observed during the reaction period. Heating for an additional hour at 135° C. also failed to generate a volatile coproduct which indicated no conversion to the desired product.
後処理
- temperatureHeating for an additional hour at 135° C.
出典と根拠
- ORDレコード
- ord-9263fd3c38db4e7d8af1acf74087dcb3
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05728878
反応ノート
読み込み中…