HCID 867097、化合物 → HCID 21942634、化合物
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:14][N:13]=[C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=3)[N:11]=2)=[CH:6][CH:5]=1)([O-])=O.[BH4-].[Na+].[S]>O1CCCC1>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:14][N:13]=[C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=3)[N:11]=2)=[CH:6][CH:5]=1参加物
5
実験手順
A solution of 2.5 g (0.01 mole) of 5-(4-nitrophenyl)-3-(2-pyridyl)-1,2,4-oxadiazole in 200 ml of tetrahydrofuran is added slowly to a solution of NaBH2S3 which is prepared by stirring 0.36 g of NaBH4 and 0.96 g of sulfur in 50 ml of tetrahydrofuran for 0.5 hour. The reaction mixture is then refluxed for 24 hours. The mixture is filtered, cooled, and the solvent is evaporated in vacuo to give 1.0 g (42% yield) of the title compound.
後処理
- customis prepared
- temperatureThe reaction mixture is then refluxed for 24 hours
- filtrationThe mixture is filtered
- temperaturecooled
- customthe solvent is evaporated in vacuo
出典と根拠
- ORDレコード
- ord-94b1003ba92d465a8cf0959f6bc6ef58
- 出典データセット
- uspto-grants-1977_05
- 特許番号
- US04022901
反応ノート
読み込み中…