Hydrochloric Acid → HCID 178510555、化合物

HRID 240307

反応式

HRID 240307 の反応式
[O:1]=[C:2]1[C:14]2[C:9](=[N:10][C:11](C#N)=[C:12]([C:15]#[N:16])[N:13]=2)[C:8]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]1=2.Cl.[OH-:20].[Na+]>>[OH:20][C:11]1[N:10]=[C:9]2[C:8]3[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=3[C:2](=[O:1])[C:14]2=[N:13][C:12]=1[C:15]#[N:16]

参加物

4

反応物 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 2929299-oxo-9H-indeno(1,2-b)pyrazine-2,3-dicarbonitrile

生成物 1

HCID 178510555HCID 178510555、化合物収率 90%

実験手順

A suspension of 1 (5.66 g, 24.3 mmol) in aqueous NaOH (2% w/v, 81 ml) was stirred at room temperature for 16 hours. The mixture was acidified with 3N HCl to pH 1, the precipitate was collected by filtration, washed with water and dried under vacuum, affording 6 (4.88 g, 90%) as light brown solid.

後処理

  1. filtrationthe precipitate was collected by filtration
  2. washwashed with water
  3. customdried under vacuum

出典と根拠

ORDレコード
ord-4af3784d1a4c4d8a8ef952e3236eaa83
出典データセット
uspto-grants-2014_02
特許番号
US08648076B2

関連ノート

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