2-Amino-5-nitrobenzoic acid → HCID 178526470、化合物
反応式
[NH2:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=O.C(O)(=O)C.[CH:18](N)=[NH:19]>COC(O)C>[N+:11]([C:8]1[CH:7]=[C:3]2[C:2](=[CH:10][CH:9]=1)[N:1]=[CH:18][N:19]=[C:4]2[OH:6])([O-:13])=[O:12]参加物
4
反応条件
- 温度
- 115 °C
実験手順
A mixture of 2-amino-5-nitrobenzoic acid (1000 g, 5 mol) and formamidine acetate (1000 g, 10 mol) were dissolved in methoxyethanol (4 L) and heated to 115° C. for 16 hours. After cooling the mixture to room temperature, ice water (5 L) was added and the mixture was stirred for 30 minutes before collecting the product (125 g, 14%) by filtration.
後処理
- temperatureAfter cooling the mixture to room temperature
- custombefore collecting the product (125 g, 14%)
- filtrationby filtration
出典と根拠
- ORDレコード
- ord-c6eaa425e0df4e24ab878d970d8aa4c3
- 出典データセット
- uspto-grants-2014_02
- 特許番号
- US08648087B2
反応ノート
読み込み中…