2-Amino-5-nitrobenzoic acid → HCID 178526470、化合物

HRID 240566

反応式

HRID 240566 の反応式
[NH2:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=O.C(O)(=O)C.[CH:18](N)=[NH:19]>COC(O)C>[N+:11]([C:8]1[CH:7]=[C:3]2[C:2](=[CH:10][CH:9]=1)[N:1]=[CH:18][N:19]=[C:4]2[OH:6])([O-:13])=[O:12]

参加物

4

反応物 2

HCID 120322-Amino-5-nitrobenzoic acidHCID 160693Formamidine acetate

生成物 1

HCID 178526470HCID 178526470、化合物

試薬・触媒・溶媒 1

HCID 30156371-Methoxyethanol溶媒

反応条件

温度
115 °C

実験手順

A mixture of 2-amino-5-nitrobenzoic acid (1000 g, 5 mol) and formamidine acetate (1000 g, 10 mol) were dissolved in methoxyethanol (4 L) and heated to 115° C. for 16 hours. After cooling the mixture to room temperature, ice water (5 L) was added and the mixture was stirred for 30 minutes before collecting the product (125 g, 14%) by filtration.

後処理

  1. temperatureAfter cooling the mixture to room temperature
  2. custombefore collecting the product (125 g, 14%)
  3. filtrationby filtration

出典と根拠

ORDレコード
ord-c6eaa425e0df4e24ab878d970d8aa4c3
出典データセット
uspto-grants-2014_02
特許番号
US08648087B2

関連ノート

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