Cysteamine Hydrochloride → HCID 178494333、化合物
反応式
ClCN1N=C(C)C=N1.S(Cl)(Cl)=O.O[CH2:14][C:15]1[S:16][CH:17]=[C:18]([CH3:20])[N:19]=1.Cl.[NH2:22][CH2:23][CH2:24][SH:25].C[O-].[Na+].[CH3:29][O:30][C:31]1[C:35](OC)=[N:34][S:33](=[O:39])(=[O:38])[N:32]=1>>[CH3:29][O:30][C:31]1[C:35]([NH:22][CH2:23][CH2:24][S:25][CH2:14][C:15]2[S:16][CH:17]=[C:18]([CH3:20])[N:19]=2)=[N:34][S:33](=[O:39])(=[O:38])[N:32]=1参加物
実験手順
When 2-chloromethyl-4-methyltriazole [prepared by the reaction of thionyl chloride and 2-hydroxymethyl-4-methylthiazole, which itself is prepared according to the procedure of J. Chem. Soc., (Suppl. Issue No. 1), S106-111 (1966) or Acta Chem. Scand., 20, 2649 (1966)] is reacted with cysteamine hydrochloride and about two equivalents of a strong base such as sodium methoxide, and the resultant amine is treated with 3,4-dimethoxy-1,2,5-thiadiazole 1,1-dioxide, there is produced 3-methoxy-4-{2-[(4-methylthiazol-2-yl)methylthio]ethylamino}-1,2,5-thiadiazole 1,1-dioxide. When the latter compound is reacted with methylamine according to the general procedure of Example 31, there is produced 3-methylamino-4-{2-[(4-methylthiazol-2-yl)methylthio]ethylamino}-1,2,5-thiadiazole 1,1-dioxide.
後処理
- customis prepared
出典と根拠
- ORDレコード
- ord-568a3d4f7cf744ee82054eb05344c88f
- 出典データセット
- uspto-grants-1984_09
- 特許番号
- US04471122
反応ノート
読み込み中…