1,3-Dibromopropane → Ethyl 1-pyridin-3-ylcyclobutane-1-carboxylate
反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH:2]=1.Br[CH2:14][CH2:15][CH2:16]Br>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2([C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH2:16][CH2:15][CH2:14]2)[CH:2]=1参加物
3
実験手順
Prepared in a similar manner to that described above by reacting ethyl 2-pyridin-3-ylacetate with 1,3-dibromopropane to give ethyl 1-pyridin-3-ylcyclobutane-1-carboxylate which was then hydrogenated to give the desired compound as a brown oil (quantitative reaction).
後処理
- customPrepared in a similar manner to that
出典と根拠
- ORDレコード
- ord-f374677e9bf0408cab463ad44f34a638
- 出典データセット
- uspto-grants-2011_06
- 特許番号
- US07964618B2
反応ノート
読み込み中…