1,3-Dibromopropane → Ethyl 1-pyridin-3-ylcyclobutane-1-carboxylate

HRID 2424928

反応式

HRID 2424928 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH:2]=1.Br[CH2:14][CH2:15][CH2:16]Br>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2([C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH2:16][CH2:15][CH2:14]2)[CH:2]=1

参加物

3

反応物 2

HCID 80011,3-DibromopropaneHCID 96490Ethyl 3-pyridylacetate

生成物 1

HCID 67246748Ethyl 1-pyridin-3-ylcyclobutane-1-carboxylate

実験手順

Prepared in a similar manner to that described above by reacting ethyl 2-pyridin-3-ylacetate with 1,3-dibromopropane to give ethyl 1-pyridin-3-ylcyclobutane-1-carboxylate which was then hydrogenated to give the desired compound as a brown oil (quantitative reaction).

後処理

  1. customPrepared in a similar manner to that

出典と根拠

ORDレコード
ord-f374677e9bf0408cab463ad44f34a638
出典データセット
uspto-grants-2011_06
特許番号
US07964618B2

関連ノート

読み込み中…