Hydrochloric Acid → HCID 57907435、化合物
反応式
[F:1][C:2]1[S:3][C:4]2[CH2:9][CH2:8][CH:7]([C:10]([O:12]CC)=[O:11])[C:5]=2[N:6]=1.[OH-].[Li+].Cl>C1COCC1.CO>[F:1][C:2]1[S:3][C:4]2[CH2:9][CH2:8][CH:7]([C:10]([OH:12])=[O:11])[C:5]=2[N:6]=1参加物
6
実験手順
To a solution of the product from step A (100 mg, 0.456 mmol) in a mixture of THF (1.5 mL) and methanol (0.5 mL) was added a solution of lithium hydroxide (0.558 mL of a 1 M soln, 0.588 mmol) and the resulting mixture stirred at room temperature for 90 mins. 1N HCl (0.558 mL, 0.558 mmol) was added and the mixture evaporated to dryness. The resulting crude product was used immediately without purification.
後処理
- customthe mixture evaporated to dryness
- customThe resulting crude product was used immediately without purification
出典と根拠
- ORDレコード
- ord-703ea41904774cc7b7747279ccc44175
- 出典データセット
- uspto-grants-2014_02
- 特許番号
- US08653260B2
反応ノート
読み込み中…