Sodium Hydroxide → 3-Phenoxybenzyl alcohol

HRID 247724

反応式

HRID 247724 の反応式
C([O:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:7]=1)(=O)C.[OH-].[Na+]>CO>[O:12]([C:8]1[CH:7]=[C:6]([CH:11]=[CH:10][CH:9]=1)[CH2:5][OH:4])[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 170904Benzenemethanol, 3-phenoxy-, 1-acetate

生成物 1

HCID 262953-Phenoxybenzyl alcohol収率 95%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

2.42 g. (0.01 mole) of 3-phenoxybenzyl acetate, 5 cm3. of methanol and 5 cm3. of 2N sodium hydroxide solution are refluxed for three hours. Then the methanol is distilled off and the organic phase is dissolved in 30 cm3. of methylene chloride, washed with 10 cm3. of 1N hydrochloric acid solution and 10 cm3. of water. 1.90 g. of 3-phenoxybenzyl alcohol are obtained. nD20 : 1.593, yield 95%.

後処理

  1. distillationThen the methanol is distilled off
  2. dissolutionthe organic phase is dissolved in 30 cm3
  3. washof methylene chloride, washed with 10 cm3

出典と根拠

ORDレコード
ord-1a6f3bb1de714fc18ae39f93cc964184
出典データセット
uspto-grants-1987_11
特許番号
US04709081

関連ノート

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