Ammonium nitrate → 1-Acetyl-5-nitroindolin-2-one
反応式
[C:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH2:6][C:5]1=[O:13])(=[O:3])[CH3:2].[N+:14]([O-])([O-:16])=[O:15].[NH4+]>S(=O)(=O)(O)O>[C:1]([N:4]1[C:12]2[C:7](=[CH:8][C:9]([N+:14]([O-:16])=[O:15])=[CH:10][CH:11]=2)[CH2:6][C:5]1=[O:13])(=[O:3])[CH3:2]参加物
4
実験手順
17.5 g (0.10 mol) of 1-acetyl-2-indolinone are dissolved in 100 ml of conc. sulphuric acid and at −10° C. 8.8 g (0.11 mol) of ammonium nitrate are added batchwise and stirred for 15 minutes. The reaction is poured onto ice water, suction filtered and washed with water. The residue is distributed in ethyl acetate/water, the combined organic extracts are dried and concentrated by evaporation.
後処理
- additionThe reaction is poured onto ice water, suction
- filtrationfiltered
- washwashed with water
- customthe combined organic extracts are dried
- concentrationconcentrated by evaporation
出典と根拠
- ORDレコード
- ord-876a4116b49845fd9885779f56dd4f70
- 出典データセット
- uspto-grants-2005_02
- 特許番号
- US06855710B2
反応ノート
読み込み中…