反応式
[NH2:1][CH2:2][C:3]([OH:5])=[O:4].C(N(C(C)C)CC)(C)C.[CH2:15]([N:27]=C=O)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26].CN(C=[O:34])C>O.O1CCCC1>[C:15]([NH:27][NH:1][CH2:2][C:3]([OH:5])=[O:4])(=[O:34])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]参加物
7
実験手順
Glycine (0.40 g, 5.25 mmol) and 0.91 mL of diisopropylethylamine (5.25 mmol) were dissolved in 4 mL DMF and 6 mL water. Dodecylisocyanate (0.72 mL, 3.0 mmol) in 7 mL tetrahydrofuran was added and the mixture was stirred for 1 h at room temperature. Water (40 mL) was added and the resulting mixture was washed with ethyl acetate twice. The aqueous layer was acidified with 6N HCl, the resulting precipitate was filtered, and then dried to provide 575 mg of the title compound.
後処理
- washthe resulting mixture was washed with ethyl acetate twice
- filtrationthe resulting precipitate was filtered
- customdried
出典と根拠
- ORDレコード
- ord-107a21eddf7c429fa48da28ebabfc9ee
- 出典データセット
- uspto-grants-2011_01
- 特許番号
- US07868135B2
関連ノート
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