Methyl iodide → 3-methyl-1,3-benzothiazol-2-imine:hydroiodide
反応式
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[NH2:10].[CH3:11][I:12]>>[IH:12].[CH3:11][N:3]1[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[S:1][C:2]1=[NH:10]参加物
3
実験手順
Benzothiazol-2-ylamine (1.0 g, 6.6 mmol) and methyl iodide (0.48 mL, 7.9 mmol) were processed as described in Example 46A to provide 1.2 g (60%) of the title compound. 1H NMR (DMSO-d6, 300 MHz) δ ppm 3.73 (s, 3 H), 7.39-7.47 (m, 1 H), 7.59 dt, J=7.8, 1.0 Hz, 1 H), 7.65-7.71 (m, 1 H), 7.99 (d, J=8.1 Hz, 1 H), 9.99 (s, 2 H); MS (DCI/NH3) m/z 165 (M+H)+.
出典と根拠
- ORDレコード
- ord-ffe85ceb564248039d7aa131b4ebfe80
- 出典データセット
- uspto-grants-2011_01
- 特許番号
- US07875639B2
反応ノート
読み込み中…