Pyridine → HCID 20165436、化合物
反応式
[CH3:1][CH:2]1[CH:9]2[CH2:10][CH:5]([C:6]([CH3:11])=[CH:7][CH2:8]2)[CH:4]([OH:12])[CH2:3]1.[C:13](OC(=O)C)(=[O:15])[CH3:14].N1C=CC=CC=1>O1CCCC1>[C:13]([O:12][CH:4]1[CH2:3][CH:2]([CH3:1])[CH:9]2[CH2:10][CH:5]1[C:6]([CH3:11])=[CH:7][CH2:8]2)(=[O:15])[CH3:14]参加物
5
実験手順
To a solution of 10 g (60.2 mmol) of 4,8-dimethylbicyclo[3.3.1]nona-7-en-2-ol [IA] in 40 ml of tetrahydrofuran were added 6.8 g (66.6 mmol) of acetic anhydride and 5.2 g (65.7 mmol) of pyridine and the resulting mixture was heated under reflux for 5 hours. After cooling, the tetrahydrofuran was distilled off, the residue was subjected to column chromatography and eluate with toluene gave 10.9 g of the title compound, which had a woody-like smell.
後処理
- temperaturethe resulting mixture was heated
- temperatureunder reflux for 5 hours
- temperatureAfter cooling
- distillationthe tetrahydrofuran was distilled off
出典と根拠
- ORDレコード
- ord-21a8455de4b441a6a36b02930fafc00f
- 出典データセット
- uspto-grants-1987_10
- 特許番号
- US04700008
反応ノート
読み込み中…