1-[2-(Benzyloxycarbonylamino)propanoyl]-2,2-dimethyl-4-imidazolidinone → 1-(2-Aminopropanoyl)-2,2-dimethyl-4-imidazolidinone
反応式
C(OC([NH:11][CH:12]([CH3:23])[C:13]([N:15]1[CH2:19][C:18](=[O:20])[NH:17][C:16]1([CH3:22])[CH3:21])=[O:14])=O)C1C=CC=CC=1.[H][H]>[Pd]>[NH2:11][CH:12]([CH3:23])[C:13]([N:15]1[CH2:19][C:18](=[O:20])[NH:17][C:16]1([CH3:22])[CH3:21])=[O:14]参加物
4
実験手順
An ethanolic solution of 1-[2-(benzyloxycarbonylamino)propanoyl]-2,2-dimethyl-4-imidazolidinone (4.9 g) containing 1 g of 5% palladium on charcoal was stirred at room temperature while hydrogen was bubbled into the solution for 1 hour. Removal of the catalyst, evaporation of the solvent, and trituration of the residue with ethyl acetate afforded the title compound as a white powder m.p. 156° C. (decomp).
後処理
- customwas bubbled into the solution for 1 hour
- customRemoval of the catalyst, evaporation of the solvent, and trituration of the residue with ethyl acetate
出典と根拠
- ORDレコード
- ord-a0051da0bff6437eb70d71b84b48fe98
- 出典データセット
- uspto-grants-1987_10
- 特許番号
- US04703054
反応ノート
読み込み中…