Sodium borohydride → HCID 15595611、化合物

HRID 256382ノート

反応式

HRID 256382 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:12]=1[S:11][CH2:10][CH2:9][C:8]2=[O:13].[BH4-].[Na+]>CO.O1CCCC1>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:12]=1[S:11][CH2:10][CH2:9][CH:8]2[OH:13]

参加物

5

反応物 2

HCID 4311764Sodium borohydrideHCID 64553542,3-Dihydro-8-methoxy-4H-1-benzothiopyran-4-one

生成物 1

HCID 15595611HCID 15595611、化合物

試薬・触媒・溶媒 2

HCID 887Methanol溶媒2 回HCID 8028Tetrahydrofuran溶媒

実験手順

89 mmol of 8-methoxy-4-thiochromanone are dissolved in 70 ml of a mixture of methanol and tetrahydrofuran (3/4). 134 mmol of sodium borohydride dissolved in 50 ml of aqueous methanol (50%) are added. After stirring for 1 hour at room temperature and then extracting with methylene chloride, the resulting product is recrystallised from a mixture of methanol and diethyl ether (1/10).

後処理

  1. additionare added
  2. extractionextracting with methylene chloride
  3. customthe resulting product is recrystallised from a mixture of methanol and diethyl ether (1/10)

出典と根拠

ORDレコード
ord-4fc7ab4f2da34affa9b199ec66ff5b1a
出典データセット
uspto-grants-1987_10
特許番号
US04703057

反応ノート

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