1-Decanol → Decyl lactate

HRID 256794

反応式

HRID 256794 の反応式
[C:1]([O:6][CH3:7])(=[O:5])[CH:2]([CH3:4])[OH:3].[CH2:8](O)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]C.[OH-].[Na+]>OS(O)(=O)=O.CO>[C:1]([O:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])(=[O:5])[CH:2]([CH3:4])[OH:3]

参加物

6

反応物 3

HCID 81741-DecanolHCID 11040Methyl LactateHCID 14798Sodium Hydroxide

生成物 1

HCID 347720Decyl lactate収率 180.9%

試薬・触媒・溶媒 2

HCID 1118Sulfuric Acid触媒HCID 887Methanol溶媒

実験手順

A 250 mL round bottom flask equipped with a spin bar and a distillation column was charged with 100 g (0.96 moles) of methyl lactate, 304.1 g (1.92 moles) of decyl alcohol, and 500 mg of H2SO4. The reaction was heated until methanol formation ceased. The reaction was then neutralized with 0.1N NaOH (100 mL) and extracted with ether. The organic layer was dried over MgSO4, filtered and dried in vacuo to give 400 g of crude mixture. The fractional distillation was carried out three times to give 98.5 g (45% yield, 100% pure by GC) of a clear colorless oil.

後処理

  1. customA 250 mL round bottom flask equipped with a spin bar
  2. distillationa distillation column
  3. extractionextracted with ether
  4. dry with materialThe organic layer was dried over MgSO4
  5. filtrationfiltered
  6. customdried in vacuo

出典と根拠

ORDレコード
ord-2f1662f043fa4ee182792689b288e74b
出典データセット
uspto-grants-1993_11
特許番号
US05260051

関連ノート

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