反応式
C([Li])CCC.[F:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[F:13].[CH3:14][Si:15]([CH3:18])([CH3:17])Cl.C1COCC1>CCCCCC.O>[F:6][C:7]1[C:8]([F:13])=[CH:9][CH:10]=[CH:11][C:12]=1[Si:15]([CH3:18])([CH3:17])[CH3:14]参加物
7
実験手順
12.5 ml of a 1.6-molar solution of n-butyllithium in hexane is added dropwise at 0° C. to a mixture of 0.02 mol of 1,2-difluorobenzene, 0.02 mol of trimethylchlorosilane and 25 ml of THF. After stirring at room temperature for 1.5 hours, the reaction mixture is poured into water, the phases are separated, and the aqueous phase is extracted with 2×50 ml of methylene chloride. Drying over magnesium sulfate, evaporation of the solvent and chromatography give the pure product.
後処理
- customthe phases are separated
- extractionthe aqueous phase is extracted with 2×50 ml of methylene chloride
- dry with materialDrying over magnesium sulfate, evaporation of the solvent and chromatography
- customgive the pure product
出典と根拠
- ORDレコード
- ord-8afda83419114c30a43bb1c65f1f85f2
- 出典データセット
- uspto-grants-1993_11
- 特許番号
- US05262556
関連ノート
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