Water → 3-Amino-2,6-dimethylphenol

HRID 258958

反応式

HRID 258958 の反応式
[CH3:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][CH:5]=[C:4]([CH3:11])[C:3]=1[OH:12].O.C(=O)([O-])[O-].[Na+].[Na+]>[Fe].C(O)(=O)C>[NH2:8][C:7]1[C:2]([CH3:1])=[C:3]([OH:12])[C:4]([CH3:11])=[CH:5][CH:6]=1

参加物

6

反応物 3

HCID 962WaterHCID 10340Sodium CarbonateHCID 814763-Nitro-2,6-xylenol

生成物 1

HCID 814773-Amino-2,6-dimethylphenol収率 62%

試薬・触媒・溶媒 2

HCID 23925Iron触媒HCID 176Acetic Acid溶媒

実験手順

157 g (0.94 mole) of 2,6-dimethyl-3-nitro phenol is added little by little, while stirring, to a reducing mixture consisting of 950 cm3 of water, 30 cm3 of acetic acid and 158 g of iron, which has first been heated to 70°. When this addition has been completed, the heating is continued for 20 minutes. The reaction mixture is then neutralized with sodium carbonate and the boiling liquid is filtered. After cooling the filtrate, drying yields 80 g of 3-amino-2,6-dimethyl phenol which, after recrystallization in benzene, melts at 104°.

後処理

  1. temperaturehas first been heated to 70°
  2. additionWhen this addition
  3. filtrationthe boiling liquid is filtered
  4. temperatureAfter cooling the filtrate
  5. customdrying

出典と根拠

ORDレコード
ord-8ba5f60dc77743459513b68ac7f17a38
出典データセット
uspto-grants-1977_07
特許番号
US04035422

関連ノート

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