Isoquinoline → HCID 21425396、化合物

HRID 258996

反応式

HRID 258996 の反応式
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][N:2]=1.[C:11]1([C:17]([CH:19]([Br:26])[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[O:18])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C1C=CC=CC=1>[Br-:26].[C:11]1([C:17]([CH:19]([C:1]2[C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH:4]=[CH:3][NH+:2]=2)[C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)=[O:18])[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

参加物

4

反応物 2

HCID 8405IsoquinolineHCID 1026302-Bromo-1,2-diphenylethan-1-one

生成物 1

HCID 21425396HCID 21425396、化合物

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

A solution of isoquinoline(10 g) and desylbromide (10 g) in dry benzene (50 ml) was stirred at 40° for seven hours. The suspension was allowed to stand overnight, and the benzene solution decanted off. The solid was ground to a powder, washed well with ether, and dried. Yield 12.3 g (85%), m.p. 239°-241° (Found C 68.3; H 4.6; N 3.4, Required C 68.3; H 4.5; N 3.5).

後処理

  1. customthe benzene solution decanted off
  2. washwashed well with ether
  3. customdried

出典と根拠

ORDレコード
ord-c0caa46ece104cd28f97510ceffa0466
出典データセット
uspto-grants-1977_07
特許番号
US04035499

関連ノート

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