Potassium Permanganate → 1,2-Benzisothiazol-3(2H)-one, 5,6-dimethoxy-, 1,1-dioxide
反応式
[CH3:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[C:5]([O:10][CH3:11])=[CH:4][C:3]=1[S:12]([NH2:15])(=[O:14])=[O:13].[Mn]([O-])(=O)(=O)=[O:17].[K+]>[OH-].[Na+]>[CH3:9][O:8][C:6]1[C:5]([O:10][CH3:11])=[CH:4][C:3]2[S:12](=[O:14])(=[O:13])[NH:15][C:1](=[O:17])[C:2]=2[CH:7]=1参加物
4
実験手順
16 gm (0.08 mol) of 2-methyl-4,5-dimethoxy-benzene sulfonamide were dissolved in 500 ml of an aqueous 5% sodium hydroxide solution, and the solution was heated at its boiling point for 2 hours after addition of 39.6 gm (0.25 mol) of potassium permanganate. After cooling, the reaction mixture was suction-filtered through celite, and the desired product was precipitated by addition of concentrated hydrochloric acid. Rf -value (benzene/acetone = 3/1): 0.2-0.4.
後処理
- temperaturethe solution was heated at its boiling point for 2 hours
- temperatureAfter cooling
- filtrationthe reaction mixture was suction-filtered through celite
- customthe desired product was precipitated by addition of concentrated hydrochloric acid
出典と根拠
- ORDレコード
- ord-607d4c508e6e4f9fac3ed66c1e40bcb9
- 出典データセット
- uspto-grants-1977_07
- 特許番号
- US04038407
反応ノート
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