Hydrochloric Acid → 3-(3-Chlorophenyl)prop-2-enoic acid
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=O.C(O)(=O)[CH2:11][C:12]([OH:14])=[O:13].N1C=CC=CC=1.Cl>O>[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=[CH:11][C:12]([OH:14])=[O:13]参加物
6
実験手順
The starting material is prepared as follows: The mixture of 50 g of 3-chlorobenzaldehyde, 41 g of malonic acid and 36 ml of pyridine is heated on the steam bath for 3 hours. The residue is dissolved in 200 ml of water, the solution acidified with hydrochloric acid, filtered, and the residue recrystallized from aqueous ethanol, to yield the 3-chlorocinnamic acid melting at 150°-152°.
後処理
- customThe starting material is prepared
- temperatureis heated on the steam bath for 3 hours
- filtrationfiltered
- customthe residue recrystallized from aqueous ethanol
出典と根拠
- ORDレコード
- ord-bdef277686ca4cf78ffde5dfc821e56d
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04147786
反応ノート
読み込み中…