Hydroxylamine → HCID 178525219、化合物

HRID 261728ノート

反応式

HRID 261728 の反応式
[C:1]12([CH2:12][C:11](=[O:13])[O:10][C:8](=[O:9])[CH2:7]1)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2.[NH2:14][OH:15].Cl.NO.C(=O)([O-])[O-].[Na+].[Na+]>>[OH:15][N:14]=[C:8]([OH:9])[CH2:7][C:1]1([CH2:12][C:11]([OH:10])=[O:13])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

5

反応物 4

HCID 787HydroxylamineHCID 10340Sodium CarbonateHCID 443297Hydroxyamine hydrochlorideHCID 27342891,1-Cyclohexanediacetic Anhydride

生成物 1

HCID 178525219HCID 178525219、化合物

反応条件

温度
70 °C

実験手順

50 g. 1,1-Cyclohexane-diacetic anhydride was introduced portionwise, while stirring, into an aqueous solution of hydroxylamine, prepared from 23.4 g. hydroxylamine hydrochloride and 21.12 g. sodium carbonate. After completion of the addition, the reaction mixture as heated for 2 hours at 70° C.; an oil separated out. After cooling, the pH was adjusted to 2 with 2N hydrochloric acid and the crystalline precipitate was filtered off with suction. The precipitate was washed with water, taken up in methanol, any undissolved material was removed and, after the addition of water, it was evaporated in a vacuum. There was obtained 45.5 g of 1,1-cyclohexane-diacetic acid N-hydroxyimide; m.p. 104° C.

後処理

  1. customprepared from 23.4 g
  2. additionAfter completion of the addition
  3. customan oil separated out
  4. temperatureAfter cooling
  5. filtrationthe crystalline precipitate was filtered off with suction
  6. washThe precipitate was washed with water
  7. customany undissolved material was removed
  8. additionafter the addition of water, it
  9. customwas evaporated in a vacuum

出典と根拠

ORDレコード
ord-718d37905d8540cfb5ac8d0f7ba1eae3
出典データセット
uspto-grants-1979_05
特許番号
US04152326

反応ノート

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