反応式
[CH2:1]([OH:4])[C:2]#[CH:3].[CH2:5]=O.[CH2:7]([NH:9][CH2:10][CH3:11])[CH3:8].[I-].[K+].S(=O)(=O)(O)O>S([O-])([O-])(=O)=O.[Cu+2].O>[CH2:7]([N:9]([CH2:10][CH3:11])[CH2:5][C:3]#[C:2][CH2:1][OH:4])[CH3:8]参加物
8
反応条件
- 温度
- 92 °C
実験手順
204 parts by weight of aqueous 55% strength propargyl alcohol, 250 parts by weight of 30% strength aqueous formaldehyde, 161 parts by weight of diethylamine, 1.4 parts by weight of copper sulfate, 2 parts by weight of potassium iodide, 50 parts by weight of water and 115 parts by weight of concentrated sulfuric acid are mixed and brought to pH 5. The mixture is heated for 5 hours at 92° C. and worked up as described. 242 parts by weight of 1-diethylaminobut-2-yn-4-ol are obtained, corresponding to a yield of 86%.
出典と根拠
- ORDレコード
- ord-947d44843c3f4b7fbab1d2263be8b0ed
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04148824
関連ノート
読み込み中…