1,3-Dibromopropane → 3-[N'-(3-Bromopropyl)-N'-methylamino]-N,N,N-trimethyl-1-propanaminium Bromide

HRID 263171ノート

反応式

HRID 263171 の反応式
[Br-].[CH3:2][N+:3]([CH3:10])([CH3:9])[CH2:4][CH2:5][CH2:6][NH:7][CH3:8].[Br:11][CH2:12][CH2:13][CH2:14]Br>C(#N)C>[Br-:11].[Br:11][CH2:12][CH2:13][CH2:14][N:7]([CH2:6][CH2:5][CH2:4][N+:3]([CH3:10])([CH3:9])[CH3:2])[CH3:8]

参加物

4

反応物 2

HCID 80011,3-DibromopropaneHCID 21444211N,N,N-Trimethyl-3-(methylamino)propan-1-aminium bromide

生成物 1

HCID 213163773-[N'-(3-Bromopropyl)-N'-methylamino]-N,N,N-trimethyl-1-propanaminium Bromide

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

To a stirred solution of 3.02 g. (14.3 mmoles) of N,N,N-trimethyl-[3-(methylamino)]-1-propanaminium bromide in 30 ml. of acetonitrile is added a solution of 2.88 g. (14.3 mmoles) of 1,3-dibromopropane and the mixture is stirred at room temperature under nitrogen for 3.5 hours. The mixture is cooled in an ice-water bath and then the insoluble material is removed by filtration. The filtrate is evaporated and dried in vacuo and is extracted with chloroform. The chloroform extract is evaporated and dried to give the product.

後処理

  1. temperatureThe mixture is cooled in an ice-water bath
  2. customthe insoluble material is removed by filtration
  3. customThe filtrate is evaporated
  4. customdried in vacuo
  5. extractionis extracted with chloroform
  6. extractionThe chloroform extract
  7. customis evaporated
  8. customdried
  9. customto give the product

出典と根拠

ORDレコード
ord-8d6d7c1ab8dd47819119c31fca3e5c6c
出典データセット
uspto-grants-1979_05
特許番号
US04156693

反応ノート

読み込み中…