Phosphorus sulfide (P2S5) → Tetradecanethioamide

HRID 264128

反応式

HRID 264128 の反応式
P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:2].[C:15]([NH2:30])(=O)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]>C1COCC1>[C:15](=[S:2])([NH2:30])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

参加物

4

反応物 2

HCID 14817Phosphorus sulfide (P2S5)HCID 69492Tetradecanamide

生成物 1

HCID 21469509Tetradecanethioamide収率 105.6%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

Phosphorus pentasulfide (9.8 g, 0.044 mol) was added to a mixture of tetradecanamide (8.6 g, 0.04 mol) in dry THF (250 mL) and the mixture refluxed overnight, concentrated in vacuo, and heated with methanol (200 mL), filtered, and the filtrate concentrated in vacuo to yield a pale yellow solid (10.28 g, 99%) used without further purification.

後処理

  1. temperaturethe mixture refluxed overnight
  2. concentrationconcentrated in vacuo
  3. temperatureheated with methanol (200 mL)
  4. filtrationfiltered
  5. concentrationthe filtrate concentrated in vacuo

出典と根拠

ORDレコード
ord-4ff015936dad43c28e0d560ebd8cf89e
出典データセット
uspto-grants-1997_07
特許番号
US05646170

関連ノート

読み込み中…