Methyl iodide → Ethyl 3-methylamino-4-cyclohexylphenylglyoxylate
反応式
[NH2:1][C:2]1[CH:3]=[C:4]([C:14](=[O:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:5]=[CH:6][C:7]=1[CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1.[CH3:21]I>N1C=CC=CC=1>[CH3:21][NH:1][C:2]1[CH:3]=[C:4]([C:14](=[O:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:5]=[CH:6][C:7]=1[CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1参加物
4
実験手順
To a solution of 0.01 moles of ethyl 3-amino-4-cyclohexylphenylglyoxylate in 100 ml. of pyridine is added 0.1 moles of methyl iodide. The reaction mixture is stirred overnight at room temperature, filtered and concentrated. The residue is distilled to obtain ethyl 3-methylamino-4-cyclohexylphenylglyoxylate.
後処理
- filtrationfiltered
- concentrationconcentrated
- distillationThe residue is distilled
出典と根拠
- ORDレコード
- ord-a2e369448a4f40eea2bd19b445797bbb
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04150148
反応ノート
読み込み中…