Ethyl bromoacetate → HCID 178472639、化合物

HRID 26700

反応式

HRID 26700 の反応式
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[N:4]=[CH:3]1.[Br:11][CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14]>CCOCC>[Br-:11].[CH2:16]([O:15][C:13]([CH2:12][N+:4]1[C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[N:2]([CH3:1])[CH:3]=1)=[O:14])[CH3:17]

参加物

4

反応物 2

HCID 7748Ethyl bromoacetateHCID 958901H-Benzimidazole, 1-methyl-

生成物 1

HCID 178472639HCID 178472639、化合物収率 62%

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒2 回

実験手順

The 1-methyl-benzimidazole of Step A was dissolved in ether and 1.4 equivalents of ethyl bromoacetate were added thereto. The ether solution was allowed to stand for several days and the crystals formed were recovered for a 62% yield of 1-ethoxycarbonylmethyl-3-methyl-benzimidazolium bromide. After crystallization from an ethyl acetate-methanol mixture, the product melted at 160°-161° C.

後処理

  1. waitto stand for several days
  2. customthe crystals formed

出典と根拠

ORDレコード
ord-1304c5c6f0684e9e96e83281b74b04e6
出典データセット
uspto-grants-1979_04
特許番号
US04151280

関連ノート

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