反応式
[CH3:1][N:2]([CH3:13])[C:3](=[O:12])[C:4](=[N:10][OH:11])[C:5](=[N:7][O:8][CH3:9])[CH3:6].[CH3:14][N:15]=[C:16]=[O:17].C1N2CCN(CC2)C1>C(Cl)Cl>[CH3:13][N:2]([CH3:1])[C:3](=[O:12])[C:4](=[N:10][O:11][C:16](=[O:17])[NH:15][CH3:14])[C:5](=[N:7][O:8][CH3:9])[CH3:6]参加物
5
反応条件
- 温度
- 25 °C
実験手順
A mixture of 34 parts of N,N-dimethyl-2-hydroxyimino-3-methoxyiminobutyramide, 350 parts of methylene chloride, 13 parts of methyl isocyanate and one-tenth part triethylenediamine was stirred at 25° C. for 3 hours and then refluxed for 1 hour. The solvent was removed by stripping under reduced pressure (15 mm.) at 50° bath temperature, thereby affording the solid crude product. Recrystallization from a benzene-acetonitrile mixture gave 32 parts of N,N-dimethyl-3-methoxyimino-2-[(methylcarbamoyl)oximino]butyramide, m.p. 172°-173° C.
後処理
- temperaturerefluxed for 1 hour
- customThe solvent was removed
- customby stripping under reduced pressure (15 mm.) at 50°
- customaffording the solid crude product
- customRecrystallization from a benzene-acetonitrile mixture
出典と根拠
- ORDレコード
- ord-515cd4a944c94100a0ce420c1a056260
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04151296
関連ノート
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