Isobutylene → Rac.-methyl 3-tert. butoxy-2-methylpropionate

反応式

[CH3:1][O:2][C:3](=[O:8])[CH:4]([CH3:7])[CH2:5][OH:6].[CH3:9][C:10](=[CH2:12])[CH3:11]>>[C:10]([O:6][CH2:5][CH:4]([CH3:7])[C:3]([O:2][CH3:1])=[O:8])([CH3:12])([CH3:11])[CH3:9]

参加物

反応物 2

HCID 8255Isobutylene

HCID 521128Methyl 3-hydroxy-2-methylpropanoate

生成物 1

HCID 12923318Rac.-methyl 3-tert. butoxy-2-methylpropionate収率 43.5%

実験手順

Treatment of rac. methyl-3-hydroxy-2-methylpropionate with isobutylene using the procedure described in Example 1 gave rac.-methyl 3-tert. butoxy-2-methylpropionate in 43.5% yield as a colorless liquid. b.p. 75°-85° C. (bath temperature) (11 mm Hg.).

出典と根拠

ORDレコード: ord-25b62f0aefa74641aa740ab860526827
出典データセット: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04151205

反応ノート

読み込み中…