Isopropylamine → HCID 58772830、化合物

HRID 271449ノート

反応式

HRID 271449 の反応式
Cl[C:2]1[N:7]2[C:8](=[O:11])[NH:9][N:10]=[C:6]2[C:5]([C:12]2[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][CH:13]=2)=[C:4]([C:19]2[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=2)[N:3]=1.[CH:26]([NH2:29])([CH3:28])[CH3:27]>C1COCC1>[Cl:25][C:22]1[CH:23]=[CH:24][C:19]([C:4]2[N:3]=[C:2]([NH:29][CH:26]([CH3:28])[CH3:27])[N:7]3[C:8](=[O:11])[NH:9][N:10]=[C:6]3[C:5]=2[C:12]2[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][CH:13]=2)=[CH:20][CH:21]=1

参加物

4

反応物 2

HCID 6363IsopropylamineHCID 587728405-chloro-7,8-bis(4-chlorophenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one

生成物 1

HCID 58772830HCID 58772830、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

To a stirring solution of 5-chloro-7,8-bis(4-chlorophenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one (39 mg, 0.10 mmol) in 1 mL THF, was added isopropylamine (18 mg, 0.30 mmol). The reaction mixture was stirred at room temperature for 1 h and then concentrated under reduced pressure. The resulting crude title compound was used in the next step without further purification.

後処理

  1. concentrationconcentrated under reduced pressure
  2. customThe resulting crude title compound was used in the next step without further purification

出典と根拠

ORDレコード
ord-fe6ed3745cb84b19b8d45685c6afdf0d
出典データセット
uspto-grants-2008_11
特許番号
US07452892B2

反応ノート

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