反応式
[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]#[N:11])=[CH:5][CH:4]=1.Br[CH2:13][CH2:14][O:15][CH2:16][CH2:17]Br.[H-].[Na+].[I-].[K+]>>[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2([C:10]#[N:11])[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)=[CH:5][CH:4]=1参加物
5
実験手順
The title compound (5.5 g, 77%, solid after trituration in pentane) was prepared using 4-(methylthio)phenylacetonitrile, bis(2-bromoethyl)ether, sodium hydride and potassium iodide similarly to the procedure used for intermediate 56. Microanalysis: Found: C, 66.62; H, 6.46; N, 5.97%. C13H15NOS requires C, 66.92; H, 6.48; N, 6.00%.
出典と根拠
- ORDレコード
- ord-d5f7c07a194b453e8a04f9ba24e4bd52
- 出典データセット
- uspto-grants-2008_11
- 特許番号
- US07456164B2
関連ノート
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