Sodium Hydroxide → Acifluorfen sodium

HRID 27319

反応式

HRID 27319 の反応式
[Cl:1][C:2]1[CH:20]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:14]([O-:16])=[O:15])=[C:9]([CH:13]=1)[C:10]([OH:12])=[O:11].[OH-].[Na+:26]>CO>[Cl:1][C:2]1[CH:20]=[C:19]([C:21]([F:22])([F:23])[F:24])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:14]([O-:16])=[O:15])=[C:9]([CH:13]=1)[C:10]([O-:12])=[O:11].[Na+:26]

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 44073Acifluorfen

生成物 1

HCID 44072Acifluorfen sodium収率 105.4%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid (1.7 g, 0.0047 mole) is dissolved in methanol (25 ml) and sodium hydroxide (4.7 ml of 1 N NaOH in methanol, 0.0047 mole) is added rapidly. The solvent is then removed in vacuo to give 1.9 g of product that decomposes at 217° C.

後処理

  1. customThe solvent is then removed in vacuo

出典と根拠

ORDレコード
ord-f721db82d1d0420393e4aedde7b519cb
出典データセット
uspto-grants-1980_09
特許番号
US04220468

関連ノート

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