2-(4-chlorobenzyl)-4,5,6,7-tetrahydro-3H-azepine → 2-[(4-Chlorophenyl)methyl]azepane

HRID 27427

反応式

HRID 27427 の反応式
[Cl:1][C:2]1[CH:15]=[CH:14][C:5]([CH2:6][C:7]2[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][N:8]=2)=[CH:4][CH:3]=1>[Pt]>[Cl:1][C:2]1[CH:15]=[CH:14][C:5]([CH2:6][CH:7]2[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][NH:8]2)=[CH:4][CH:3]=1

参加物

3

反応物 1

HCID 233428152-(4-chlorobenzyl)-4,5,6,7-tetrahydro-3H-azepine

生成物 1

HCID 39338092-[(4-Chlorophenyl)methyl]azepane

試薬・触媒・溶媒 1

HCID 23939Platinum触媒

実験手順

Hydrogenate the thus-obtained 2-(4-chlorobenzyl)-4,5,6,7-tetrahydro-3H-azepine with platinum/active carbon/ hydrogen. Filter out the catalyst, concentrate the filtrate and distil to obtain 61.9 g (68% of theory) of the title compound with a BP of 93° at 0.1 mm of Hg.

後処理

  1. filtrationFilter out the catalyst
  2. concentrationconcentrate the filtrate
  3. customdistil

出典と根拠

ORDレコード
ord-a9a8a7247d0e458c9769f6464a652878
出典データセット
uspto-grants-1980_09
特許番号
US04221788

関連ノート

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