Thionyl Chloride → 2-(7-Methoxynaphthalen-1-yl)acetyl chloride
反応式
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([OH:16])=O)=[CH:5][CH:4]=1.S(Cl)([Cl:19])=O>C(Cl)(Cl)Cl>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([Cl:19])=[O:16])=[CH:5][CH:4]=1参加物
4
実験手順
The 7-methoxynaphth-1-ylacetic acid obtained above is dissolved, while warm, in 300 cm3 of chloroform. The mixture is heated to reflux, and then thionyl chloride is added dropwise. The mixture is refluxed for two hours and evaporated to dryness, yielding an oil which crystallises by cooling. The resulting residue is used as such in the following step.
後処理
- dissolutionis dissolved
- temperatureThe mixture is heated
- temperatureto reflux
- temperatureThe mixture is refluxed for two hours
- customevaporated to dryness
- customyielding an oil which
- customcrystallises
- temperatureby cooling
出典と根拠
- ORDレコード
- ord-68b8a011210c4d8fbc1f976d53140819
- 出典データセット
- uspto-grants-1995_02
- 特許番号
- US05389683
反応ノート
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