反応式
O[CH2:2][C@@H:3]([NH2:8])[CH2:4][CH:5]([CH3:7])[CH3:6].O=S(Cl)Cl.[C:13]([C:15]1[CH:20]=[CH:19][C:18]([N:21]=[C:22]=[S:23])=[C:17]([CH2:24][CH3:25])[CH:16]=1)#[N:14]>>[C:13]([C:15]1[CH:20]=[CH:19][C:18]([N:21]=[C:22]2[NH:8][C@@H:3]([CH2:4][CH:5]([CH3:7])[CH3:6])[CH2:2][S:23]2)=[C:17]([CH2:24][CH3:25])[CH:16]=1)#[N:14]参加物
4
実験手順
(1S)-1-(Hydroxymethyl)-3-methylbutylamine was reacted with SOCl2 followed by 4-cyano-2-ethylphenyl isothiocyanate according to Method C2a to give (4S)-2-(4-cyano-2-ethylphenylimino)-4-isobutyl-1,3-thiazolidine. The thiazolidine was reacted with isobutyl bromide according to Method D2a to give (4S)-2-(4-cyano-2-ethylphenylimino)-3,4-diisobutyl-1,3-thiazolidine.
出典と根拠
- ORDレコード
- ord-729bc953ecec46e080796b4cb27e7f59
- 出典データセット
- uspto-grants-2002_03
- 特許番号
- US06353006B1
関連ノート
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