1,1'-Carbonyldiimidazole → 5-Pyrimidyl carboxylic acid imidazolide
反応式
[N:1]1[CH:6]=[C:5]([C:7]([OH:9])=[O:8])[CH:4]=[N:3][CH:2]=1.C(N1C=CN=C1)(N1C=CN=C1)=O>C(Cl)Cl>[N-:3]1[CH:5]=[CH:6][N:1]=[CH:2]1.[N:1]1[CH:6]=[C:5]([C:7]([OH:9])=[O:8])[CH:4]=[N:3][CH:2]=1参加物
4
実験手順
5-pyrimidyl carboxylic acid, 1.9 gm, was added to 30 ml of methylene chloride. 2.4 gm of carbonyldiimidazole was added to the system. The system was stirred at room temperature for 3 hours to form the 5-pyrimidyl carboxylic acid imidazolide.
出典と根拠
- ORDレコード
- ord-45c587997494432c87f23050fd22982c
- 出典データセット
- uspto-grants-1986_05
- 特許番号
- US04588735
反応ノート
読み込み中…