1,1'-Carbonyldiimidazole → 5-Pyrimidyl carboxylic acid imidazolide

HRID 280244

反応式

HRID 280244 の反応式
[N:1]1[CH:6]=[C:5]([C:7]([OH:9])=[O:8])[CH:4]=[N:3][CH:2]=1.C(N1C=CN=C1)(N1C=CN=C1)=O>C(Cl)Cl>[N-:3]1[CH:5]=[CH:6][N:1]=[CH:2]1.[N:1]1[CH:6]=[C:5]([C:7]([OH:9])=[O:8])[CH:4]=[N:3][CH:2]=1

参加物

4

反応物 2

HCID 682631,1'-CarbonyldiimidazoleHCID 78346Pyrimidine-5-carboxylic acid

生成物 1

HCID 867399665-Pyrimidyl carboxylic acid imidazolide

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

5-pyrimidyl carboxylic acid, 1.9 gm, was added to 30 ml of methylene chloride. 2.4 gm of carbonyldiimidazole was added to the system. The system was stirred at room temperature for 3 hours to form the 5-pyrimidyl carboxylic acid imidazolide.

出典と根拠

ORDレコード
ord-45c587997494432c87f23050fd22982c
出典データセット
uspto-grants-1986_05
特許番号
US04588735

関連ノート

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