Chloride → 5-Bromo-1-methyl-3-(2-(oxetan-3-yl)-1,2,3,4-tetrahydroisoquinolin-6-ylamino)pyrazin-2(1H)-one

反応式

[Br:1][c:2]1[n:3][c:4]([NH:10][c:11]2[cH:12][c:13]3[c:18]([cH:19][cH:20]2)[CH2:17][NH:16][CH2:15][CH2:14]3)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1.[C:26]([BH3-:27])#[N:28].[CH3:30][OH:31].[Cl-:32].[Cl-:34].[Na+:29].[O:21]1[CH2:22][C:23](=[O:25])[CH2:24]1.[Zn+2:33]>>[Br:1][c:2]1[n:3][c:4]([NH:10][c:11]2[cH:12][c:13]3[c:18]([cH:19][cH:20]2)[CH2:17][N:16]([CH:23]2[CH2:22][O:21][CH2:24]2)[CH2:15][CH2:14]3)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1