Sodium Hydroxide → HCID 178418387、化合物
反応式
[CH3:1][N:2]([CH3:9])[C:3](=[O:8])[CH2:4][C:5](=[O:7])[CH3:6].[OH-].[Na+].[Cl-].[C:13]1([N+:19]#[N:20])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>O>[CH3:1][N:2]([CH3:9])[C:3](=[O:8])[C:4](=[N:20][NH:19][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:5](=[O:7])[CH3:6]参加物
5
実験手順
4.5 g (0.035 mol) of N,N-dimethyl-3-oxobutyramide, a solution of 4.9 g (0.122 mol) of NaOH in 45 ml of water and 0.037 mol of phenyldiazonium chloride were treated as described in preparation 8. The crude reaction mixture was purified by chromatography on silica gel (hexane/Et2O 0%→100%) obtaining 3.5 g of the title compound which was used as such in the subsequent step. M.p.=131°-133° C.
後処理
- customas described in preparation 8
- customThe crude reaction mixture
- customwas purified by chromatography on silica gel (hexane/Et2O 0%→100%)
出典と根拠
- ORDレコード
- ord-b070703fd73b4d8680fe6f71c91c67d7
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05731322
反応ノート
読み込み中…