Methane → 4-amino-N-(4,4-difluorocyclohexyl)bicyclo[2.2.2]octane-1-carboxamide

反応式

[C:38].[CH2:1]([O:2][C:3](=[O:4])[NH:11][C:12]12[CH2:13][CH2:14][C:15]([C:20](=[O:21])[NH:22][CH:23]3[CH2:24][CH2:25][C:26]([F:29])([F:30])[CH2:27][CH2:28]3)([CH2:16][CH2:17]1)[CH2:18][CH2:19]2)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1.[H:31][H:32].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1.[Pd:39]>>[NH2:11][C:12]12[CH2:13][CH2:14][C:15]([C:20](=[O:21])[NH:22][CH:23]3[CH2:24][CH2:25][C:26]([F:29])([F:30])[CH2:27][CH2:28]3)([CH2:16][CH2:17]1)[CH2:18][CH2:19]2