2-Phenylisobutyric acid → 2-Methyl-2-phenylpropanoyl chloride
反応式
[CH3:1][C:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([CH3:6])[C:3](O)=[O:4].C(Cl)(=O)C([Cl:16])=O>ClCCl>[CH3:1][C:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([CH3:6])[C:3]([Cl:16])=[O:4]参加物
4
実験手順
A solution of 2-Methyl-2-phenylpropionic acid (10 mmol, 1.0 eq.) and oxalyl chloride (40 mmol, 4.0 eq.) in dichloromethane (30 mL) was stirred at room temperature for 18 h. The mixture was concentrated in vacuo to afford the title compound as a yellow oil.
後処理
- concentrationThe mixture was concentrated in vacuo
出典と根拠
- ORDレコード
- ord-b388f55835f0450eb8040b6671d8a7a3
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07420055B2
反応ノート
読み込み中…