Benzoyl Peroxide → Ethyl 3-bromo-4-(bromomethyl)benzoate
反応式
[Br:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][C:12]=1[CH3:13])[C:5]([O:7][CH2:8][CH3:9])=[O:6].C1C(=O)N([Br:21])C(=O)C1.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][C:12]=1[CH2:13][Br:21])[C:5]([O:7][CH2:8][CH3:9])=[O:6]参加物
5
実験手順
A mixture of 1.0 mmol of ethyl 3-bromo-4-methylbenzoate, 1.0 mmol NBS, and 0.02 mmol benzoyl peroxide in 5 mL CCl4 was refluxed for 4 h and then processed by filtration and chromatography to provide ethyl 3-bromo-4-bromomethylbenzoate as an oil.
後処理
- temperaturewas refluxed for 4 h
- filtrationprocessed by filtration and chromatography
出典と根拠
- ORDレコード
- ord-43fc139c41d84237a967f7fa62214d1c
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05731432
反応ノート
読み込み中…