3-Iodo-4-methylbenzaldehyde → 3-Iodo-4-methylstyrene
反応式
[I:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[CH3:10])[CH:5]=O.[Li][CH2:12]CCC>[Br-].C[P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.C1COCC1>[I:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[CH3:10])[CH:5]=[CH2:12]参加物
5
実験手順
This aldehyde (1 mmol)was added to a premixed solution of 1.5 mmol of methyl triphenylphosphonium bromide and 1.2 mmol of n-BuLi in 5 mL of THF at 0° C. and this mixture was stirred for 3-6 h at rt and then processed by extraction and chromatography to give 3-iodo-4-methylstyrene.
後処理
- extractionprocessed by extraction and chromatography
出典と根拠
- ORDレコード
- ord-e65eb05600a341c1a97cfb8e1984da81
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05731432
反応ノート
読み込み中…