4-Methoxybenzohydrazide → HCID 178491626、化合物

HRID 29812

反応式

HRID 29812 の反応式
[Na].Cl.[C:3](=[NH:8])(OCC)[CH3:4].[CH3:9][O:10][C:11]1[CH:20]=[CH:19][C:14]([C:15]([NH:17][NH2:18])=[O:16])=[CH:13][CH:12]=1>C(O)C>[NH:8]=[C:3]([NH:18][NH:17][C:15](=[O:16])[C:14]1[CH:13]=[CH:12][C:11]([O:10][CH3:9])=[CH:20][CH:19]=1)[CH3:4]

参加物

5

反応物 3

HCID 767924-MethoxybenzohydrazideHCID 2724290Ethanimidic acid, ethyl ester, hydrochloride (1:1)HCID 5360545Sodium

生成物 1

HCID 178491626HCID 178491626、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒2 回

実験手順

4.6 g (0.20 mol) sodium in 200 mL ethanol are combined at ambient temperature with a solution of 25 g (0.20 mol) ethyl acetimidate hydrochloride in 200 mL ethanol. The sodium chloride precipitated is suction filtered and 33.2 g (0.20 mol) 4-methoxybenzoic acid hydrazide are added to the filtrate. The reaction mixture is stirred overnight at ambient temperature and then cooled. The precipitate formed is separated off and washed with ethanol and diethyl ether. Yield: 33.6 g (81%); melting range=179-181° C.

後処理

  1. customThe sodium chloride precipitated
  2. filtrationfiltered
  3. temperaturecooled
  4. customThe precipitate formed
  5. customis separated off
  6. washwashed with ethanol and diethyl ether

出典と根拠

ORDレコード
ord-6ce67abe01174be09ba2b5676c9ac2f4
出典データセット
uspto-grants-2008_09
特許番号
US07423036B2

関連ノート

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