4-Methoxybenzohydrazide → HCID 178491626、化合物
反応式
[Na].Cl.[C:3](=[NH:8])(OCC)[CH3:4].[CH3:9][O:10][C:11]1[CH:20]=[CH:19][C:14]([C:15]([NH:17][NH2:18])=[O:16])=[CH:13][CH:12]=1>C(O)C>[NH:8]=[C:3]([NH:18][NH:17][C:15](=[O:16])[C:14]1[CH:13]=[CH:12][C:11]([O:10][CH3:9])=[CH:20][CH:19]=1)[CH3:4]参加物
5
実験手順
4.6 g (0.20 mol) sodium in 200 mL ethanol are combined at ambient temperature with a solution of 25 g (0.20 mol) ethyl acetimidate hydrochloride in 200 mL ethanol. The sodium chloride precipitated is suction filtered and 33.2 g (0.20 mol) 4-methoxybenzoic acid hydrazide are added to the filtrate. The reaction mixture is stirred overnight at ambient temperature and then cooled. The precipitate formed is separated off and washed with ethanol and diethyl ether. Yield: 33.6 g (81%); melting range=179-181° C.
後処理
- customThe sodium chloride precipitated
- filtrationfiltered
- temperaturecooled
- customThe precipitate formed
- customis separated off
- washwashed with ethanol and diethyl ether
出典と根拠
- ORDレコード
- ord-6ce67abe01174be09ba2b5676c9ac2f4
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07423036B2
反応ノート
読み込み中…