Sodium Carbonate → (+/-)-1-(Oxiranylmethyl)-2,4-imidazolidinedione
反応式
[CH2:1]([N:4]1[CH2:8][C:7](=[O:9])[NH:6][C:5]1=[O:10])[CH:2]=[CH2:3].ClC1C=C(C(OO)=[O:19])C=CC=1.S(=O)(O)[O-].C([O-])([O-])=O.[Na+].[Na+]>C(Cl)Cl>[O:19]1[CH2:3][CH:2]1[CH2:1][N:4]1[CH2:8][C:7](=[O:9])[NH:6][C:5]1=[O:10]参加物
6
実験手順
A reaction solution of 1-(2-propenyl)-2,4-imidazolidinedione (0.036 mol) and 3-chloro-benzenecarboperoxoic acid (0.043 mol, 70.75%) in DCM (25 ml) was stirred for 2 hours at room temperature. An aqueous solution of bisulfite was added and the mixture was stirred for 10 minutes. Na2CO3 was added and this mixture was extracted with DCM. The separated organic layer was dried, filtered and the solvent evaporated, yielding 5 g of (±)-1-(oxiranylmethyl)-2,4-imidazolidinedione (intermediate 18).
後処理
- extractionthis mixture was extracted with DCM
- customThe separated organic layer was dried
- filtrationfiltered
- customthe solvent evaporated
出典と根拠
- ORDレコード
- ord-2d6311f3fe124212b3572c7a948ab5ac
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07423048B2
反応ノート
読み込み中…