4-Hydroxybenzaldehyde → 4,4'-(Propane-1,3-diylbis(oxy))dibenzaldehyde

HRID 3025

反応式

HRID 3025 の反応式
[OH:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.Br[CH2:11][CH2:12][CH2:13]Br>C(=O)([O-])[O-].[K+].[K+].CN(C=O)C>[CH:6]([C:5]1[CH:8]=[CH:9][C:2]([O:1][CH2:11][CH2:12][CH2:13][O:1][C:2]2[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=2)=[CH:3][CH:4]=1)=[O:7]

参加物

5

反応物 2

HCID 1264-HydroxybenzaldehydeHCID 80011,3-Dibromopropane

生成物 1

HCID 64229124,4'-(Propane-1,3-diylbis(oxy))dibenzaldehyde収率 76%

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide溶媒HCID 11430Potassium Carbonate溶媒

実験手順

10.0 g of 4-hydroxybenzaldehyde and 8.3 g of 1,3-dibromopropane were reacted for 24 hours in 6.2 g of potassium carbonate solution in 100 ml of DMF under reflux. The reaction mixture was poured into cold distilled water to obtain a precipitate. After filtration and vacuum drying the precipitate, the resultant was recrystallized in ethanol to obtain the white product (XII-1). The product yield was 76%.

後処理

  1. temperatureunder reflux
  2. additionThe reaction mixture was poured
  3. distillationinto cold distilled water
  4. customto obtain a precipitate
  5. filtrationAfter filtration and vacuum
  6. customdrying the precipitate
  7. customthe resultant was recrystallized in ethanol
  8. customto obtain the white product (XII-1)

出典と根拠

ORDレコード
ord-db854b27d2914399bbe5f288a9a9adb4
出典データセット
uspto-grants-1998_03
特許番号
US05731599

関連ノート

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