Cyclooctylamine → 1,3,5-Benzenetricarboxylic acid tris(cyclooctylamide)

HRID 30398

反応式

HRID 30398 の反応式
[CH:1]1([NH2:9])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Li+].[Cl-].C[N:13]1[C:17](=O)[CH2:16][CH2:15][CH2:14]1.[C:19]1([C:31](Cl)=[O:32])[CH:24]=[C:23]([C:25](Cl)=[O:26])[CH:22]=[C:21]([C:28](Cl)=[O:29])[CH:20]=1>N1C=CC=CC=1>[CH:1]1([NH:9][C:31]([C:19]2[CH:24]=[C:23]([C:25]([NH:9][CH:1]3[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]3)=[O:26])[CH:22]=[C:21]([C:28]([NH:13][CH:17]3[CH2:16][CH2:15][CH2:14][CH2:3][CH2:2][CH2:1][CH2:8]3)=[O:29])[CH:20]=2)=[O:32])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

6

反応物 4

HCID 2903CyclooctylamineHCID 13387N-methyl-2-pyrrolidoneHCID 78138Trimesoyl chlorideHCID 433294Lithium Chloride

生成物 1

HCID 597896131,3,5-Benzenetricarboxylic acid tris(cyclooctylamide)

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

反応条件

温度
5 °C

実験手順

4.20 g (33 mmol) of cyclooctylamine and 0.1 g of dry LiCl are added under inert atmosphere to 70 ml of dry NMP and 15 ml of dry pyridine and cooled to 5° C. Then, 2.39 g (9 mmol) of 1,3,5-benzenetricarboxylic acid trichloride are added. The reaction mixture is heated to 75° C. and stirred. After 2 hours the reaction mixture is added to 300 ml of ice water. Customary work-up (recrystallization from N,N-dimethylformamide) gives 1,3,5-benzenetricarboxylic acid tris(cyclooctylamide).

後処理

  1. temperatureThe reaction mixture is heated to 75° C.
  2. customCustomary work-up (recrystallization from N,N-dimethylformamide)

出典と根拠

ORDレコード
ord-0249888884cf4a97b3e2384f1b38319c
出典データセット
uspto-grants-2008_09
特許番号
US07423088B2

関連ノート

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