Tetrahydrofuran → N-(1-{2-[3-(2-Methyl-quinolin-4-yl)-ureido]-ethyl}-piperidin-4-yl)-4-trifluoromethyl-benzenesulfonamide

反応式

[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH:39]([N:40]([CH2:41][CH3:42])[CH:43]([CH3:44])[CH3:45])([CH3:46])[CH3:47].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([S:9](=[O:10])(=[O:11])[Cl:12])[cH:7][cH:8]1)([F:13])[F:14].[NH2:15][CH:16]1[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][NH:24][C:25](=[O:26])[NH:27][c:28]2[cH:29][c:30]([CH3:38])[n:31][c:32]3[cH:33][cH:34][cH:35][cH:36][c:37]23)[CH2:20][CH2:21]1>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([S:9](=[O:10])(=[O:11])[NH:15][CH:16]2[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][NH:24][C:25](=[O:26])[NH:27][c:28]3[cH:29][c:30]([CH3:38])[n:31][c:32]4[cH:33][cH:34][cH:35][cH:36][c:37]34)[CH2:20][CH2:21]2)[cH:7][cH:8]1)([F:13])[F:14]