Diglycolamine → N-(2-hydroxyethoxyethyl)hexahydrophthalimide
反応式
[NH2:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][OH:7].[C:8]1(=O)[O:13][C:11](=[O:12])[CH:10]2[CH2:14][CH2:15][CH2:16][CH2:17][CH:9]12>C(O)C>[OH:7][CH2:6][CH2:5][O:4][CH2:3][CH2:2][N:1]1[C:11](=[O:12])[CH:10]2[CH2:14][CH2:15][CH2:16][CH2:17][CH:9]2[C:8]1=[O:13]参加物
4
実験手順
A 500-ml, two necked flask was equipped with a magnetic stirring bar, heating mantle and condenser. The flask was charged with 51 g of 2-(aminoethoxy) ethanol (0.49 mol.) and 250 ml of ethanol. Next, 75 g of hexahydrophthalic anhydride (0.49 mol.) was slowly added to the flask. After the addition was complete the reaction was refluxed for 12 hours. The IR spectrum indicated the reaction was complete. The ethanol was removed with a rotoevaporator to yield 113 g (96%) of N-(2-hydroxyethoxyethyl)hexahydrophthalimide.
後処理
- customA 500-ml, two necked flask was equipped with a magnetic stirring bar
- temperatureheating mantle and condenser
- additionAfter the addition
- temperaturewas refluxed for 12 hours
- customThe ethanol was removed with a rotoevaporator
出典と根拠
- ORDレコード
- ord-0a1e984cbfd144cd8fa2cccd3f2e67f2
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05733648
反応ノート
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