2-(Benzyloxy)benzaldehyde → HCID 22009001、化合物

HRID 322021

反応式

HRID 322021 の反応式
[CH2:1]([O:8][C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH:11]=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:17]([Mg]Br)=[CH2:18]>C1COCC1>[CH2:1]([O:8][C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH:11]([OH:12])[CH:17]=[CH2:18])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

4

反応物 2

HCID 3447842-(Benzyloxy)benzaldehydeHCID 178418507HCID 178418507、化合物

生成物 1

HCID 22009001HCID 22009001、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

2-(benzyloxy)benzaldehyde (5g, 23.6 mmol) was reacted with vinylmagnesium bromide in THF (90 ml) at 0 C. The reaction was quenched with 2 N HCl and the product was extracted in i-PrOAc, dried over Na2SO4 and purified by flash chromatography with EtOAc:toluene 2.5:97.5.

後処理

  1. customThe reaction was quenched with 2 N HCl
  2. extractionthe product was extracted in i-PrOAc
  3. dry with materialdried over Na2SO4
  4. custompurified by flash chromatography with EtOAc:toluene 2.5:97.5

出典と根拠

ORDレコード
ord-a4708b1709d247f8a0d9098dd75df039
出典データセット
uspto-grants-2001_04
特許番号
US06211197B1

関連ノート

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