3-Thiophen-2-ylprop-2-enoic acid → 3-(2-Thienyl)propanoic acid
反応式
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]=[CH:7][C:8]([OH:10])=[O:9]>C(O)C.[Pd]>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][CH2:7][C:8]([OH:10])=[O:9]参加物
4
実験手順
To a solution of 3-(2-thienyl)acrylic acid (7 g) in ethanol was added 5% palladium on carbon and the mixture was hydrogenated at 50 psi in a Parr apparatus. The catalyst was filtered off and the solvent was removed by evaporation to yield the title compound (5.5 g) as an oil. Electrospray MS m/z 155 [M−H]+.
後処理
- filtrationThe catalyst was filtered off
- customthe solvent was removed by evaporation
出典と根拠
- ORDレコード
- ord-1d78723a0ed54ea097bab6291d5bbe04
- 出典データセット
- uspto-grants-2001_04
- 特許番号
- US06218538B1
反応ノート
読み込み中…