Thionyl Chloride → HCID 53790015、化合物

HRID 326509

反応式

HRID 326509 の反応式
[CH2:1](O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH:9]=[CH2:10].S(Cl)([Cl:14])=O>N1C=CC=CC=1.ClCCl>[Cl:14][CH:10]=[CH:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][CH3:1]

参加物

5

反応物 2

HCID 24386Thionyl Chloride2 回HCID 256129-Decen-1-ol

生成物 1

HCID 53790015HCID 53790015、化合物収率 95.3%

試薬・触媒・溶媒 2

HCID 1049Pyridine触媒HCID 6344Dichloromethane溶媒

実験手順

To 26.0 g of 9-decene-1-ol was added 10 drops of pyridine, and the mixture was placed into an eggplant flask. To the mixture was added dropwise 24.0 g of thionyl chloride, during cooling with ice. After dropping thionyl chloride, reaction was carried out for 8.5 hours at 70° C. After conclusion of the reaction, the reaction solution was diluted with dichloromethane, and then washed with an aqueous potassium carbonate. The washed solution was dried on magnesium sulfate, and then concentrated under reduced pressure. The resulting residue was purified by column chromatography to obtain 27.7 g of 1-chloro-1-decene. (Yield: 95%)

後処理

  1. customthe mixture was placed into an eggplant flask
  2. temperatureduring cooling with ice
  3. customAfter conclusion of the reaction
  4. washwashed with an aqueous potassium carbonate
  5. customThe washed solution was dried on magnesium sulfate
  6. concentrationconcentrated under reduced pressure
  7. customThe resulting residue was purified by column chromatography

出典と根拠

ORDレコード
ord-28b42aef4a9b407bad0138984f11f0b7
出典データセット
uspto-grants-1993_12
特許番号
US05269963

関連ノート

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